美国哈佛大学医学院儿童医院神经系统科学博士后职位

2015-02-27 20:27 来源: 未知 作者: liuxuehr

Postdoctoral Positions in Neuroscience

Job Description

 

Postdoctoral Position in Neuroscience
Harvard Medical School
Dr. Xianhua PIao’s laboratory at Boston Children’s Hospital, Harvard Medical School seeks postdoctoral fellows to study adhesion G protein-coupled receptors (GPCRs) and their binding partners in glia development and diseases. The family of adhesion GPCRs is the second largest family of GPCRs with 33 members in the human genome. This class of receptors plays critically important roles in brain development, myelination, synapse pruning, and blood brain barrier formation. Mutations in multiple members of this receptor family cause human diseases; however, they remain significantly understudied and the vast majority of family members are still considered orphan receptors. Being one of the leaders in the field of adhesion GPCRs, the Piao lab and colleagues have linked adhesion GPCRs to human brain malformation (Piao et al, Science 2004), demonstrated their roles in CNS and PNS myelination (Giera et al, Nature Communications 2015; Petersen et al, Neuron 2015). To date, only 6 out of the 33 members of adhesion GPCRs have known ligand(s), two of which were de-orphaned by the Piao lab and her collaborators (Luo et al, PNAS 2011; Petersen et al, Neuron 2015). To expand this exciting lead, the Piao lab is looking for postdoctoral candidates with a strong background in biochemistry, molecular biology, and neuroscience. Successful candidates will apply their knowledge in biochemistry, histology, and mouse brain development to investigate how adhesion GPCRs and their binding partners regulate glial cell function in synapse elimination and myelination during normal development and disease conditions. An outstanding salary and benefits package is included; salary will be commensurate with experience.

声明：凡本网注明"来源：XXX"的文/图等稿件，本网转载出于传递更多信息及方便产业探讨之目的，并不意味着本站赞同其观点或证实其内容的真实性，文章内容仅供参考。如其他媒体、网站或个人从本网站转载使用，须保留本网站注明的“来源”，并自负版权等法律责任。作者如果不希望被转载或者联系转载等事宜，请与我们联系。

微信公众号

高校博士后招聘

+more

科研机构博士后招聘

+more

企事业单位博士后招聘

+more